Protein Expression Market Size, Share, Trends, Growth Outlook

Protein Expression Market is estimated to increase at a Compounded Annual Growth Rate of 12.5% CAGR over the forecast period from 2024 to 2030

The Protein Expression Market study analyzes and forecasts the market size across 6 regions and 24 countries for diverse segments- By System (Mammalian cell expression systems, Prokaryotic expression systems, Insect cell expression systems, Yeast expression systems, Cell-free expression systems, Algal-based expression systems), By Application (Therapeutic, Research, Industrial), By End-User (Pharmaceutical companies, CROs and CDMOs, Research Institutes, Others).

An Introduction to Protein Expression Market in 2024

Protein expression is the process by which a gene's DNA sequence is used to synthesize proteins within a cell, organism, or in vitro expression system. In 2024, the market for protein expression technologies continues to grow, driven by the increasing demand for recombinant proteins in research, drug discovery, and biopharmaceutical production, as well as advancements in gene editing, synthetic biology, and protein engineering techniques. Protein expression systems encompass a variety of host organisms, including bacteria, yeast, insect cells, mammalian cells, and cell-free systems, each offering unique advantages in terms of protein yield, post-translational modifications, and scalability. These expression systems are used to produce a wide range of proteins, including enzymes, antibodies, hormones, and therapeutic proteins, for applications such as structural biology, functional studies, drug screening, and protein-based therapies. With advancements in genetic engineering, expression vector design, and fermentation technologies, protein expression technologies offer improved efficiency, productivity, and cost-effectiveness for generating recombinant proteins at industrial scales. Moreover, the development of novel expression hosts, protein purification methods, and protein refolding techniques expands the repertoire of proteins that can be produced recombinantly, enabling the production of complex and challenging proteins for research and therapeutic applications. As the demand for recombinant proteins continues to grow in diverse scientific and industrial sectors, protein expression technologies play a critical role in driving innovation, advancing scientific discovery, and addressing unmet medical needs in healthcare.

Market Trend: Increasing Demand for Recombinant Proteins in Biopharmaceuticals

In the protein expression market, a prominent trend is the increasing demand for recombinant proteins in biopharmaceuticals. Recombinant protein expression systems play a crucial role in producing therapeutic proteins, such as monoclonal antibodies, cytokines, and growth factors, for use in biologics manufacturing. With the rising prevalence of chronic diseases and the growing pipeline of biologic drugs, there's a surge in demand for recombinant proteins as key components of biopharmaceutical formulations. This trend reflects the shift towards biologics-based therapies and the need for scalable protein expression platforms that offer high yields, purity, and product consistency to meet the requirements of biopharmaceutical production.

Market Driver: Advancements in Gene Editing and Synthetic Biology Technologies

A key driver propelling the growth of the protein expression market is the continuous advancements in gene editing and synthetic biology technologies. Recent innovations in gene editing tools, such as CRISPR-Cas9, zinc finger nucleases (ZFNs), and transcription activator-like effector nucleases (TALENs), have revolutionized the field of molecular biology, enabling precise manipulation of the genome for protein expression optimization. Moreover, synthetic biology approaches, including gene synthesis, pathway engineering, and cell-free protein synthesis, offer versatile platforms for designing and engineering novel protein expression systems with enhanced productivity, specificity, and functionality. These technological advancements empower researchers and biopharmaceutical companies to overcome bottlenecks in protein expression, streamline biologics development processes, and accelerate the translation of promising therapeutic candidates from bench to bedside.

Market Opportunity: Expansion into Industrial Enzyme Production and Biocatalysis

An emerging opportunity in the protein expression market lies in the expansion into industrial enzyme production and biocatalysis applications. Enzymes play critical roles in various industrial processes, including food and beverage production, biofuel synthesis, and pharmaceutical manufacturing. Protein expression systems, such as microbial fermentation and cell-free systems, offer efficient platforms for producing recombinant enzymes with tailored properties, such as substrate specificity, stability, and catalytic efficiency. With increasing demand for sustainable and eco-friendly manufacturing processes, there's a growing interest in biocatalysis as a green alternative to traditional chemical synthesis methods. By leveraging protein expression technologies and enzyme engineering strategies, companies can capitalize on the opportunity to develop novel biocatalysts, enzyme-based bioproducts, and enzyme-enabled processes that address industry needs for cost-effective, environmentally friendly solutions while driving revenue growth in the expanding market for industrial enzymes.

Protein Expression Market Share Analysis: Mammalian Cell Expression Systems is the fastest growing segment over the forecast period to 2030

Among the provided segments, Mammalian Cell Expression Systems are the fastest growing in the Protein Expression Market. This growth can be attributed to several factors. Firstly, mammalian cell expression systems offer advantages such as the ability to produce complex proteins with proper folding, post-translational modifications, and biological activity, making them indispensable for therapeutic protein production. Additionally, the increasing demand for biologics, including monoclonal antibodies, recombinant proteins, and viral vectors, in the pharmaceutical industry drives the adoption of mammalian cell expression systems due to their compatibility with human protein production and the ability to produce biologically relevant proteins. Furthermore, advancements in mammalian cell culture techniques, genetic engineering tools, and bioprocess optimization strategies have improved protein expression yields and production efficiency, enhancing the attractiveness of mammalian cell expression systems for biopharmaceutical manufacturing. Moreover, the expanding pipeline of biologic drugs and the trend towards personalized medicine further propel the demand for mammalian cell expression systems in therapeutic protein production. As a result, Mammalian Cell Expression Systems emerge as the fastest growing segment in the Protein Expression Market, addressing the evolving needs of pharmaceutical companies, contract research organizations (CROs) and contract development and manufacturing organizations (CDMOs), and research institutes effectively.

Protein Expression Competitive Analysis

The market research study provides in-depth insights into leading companies including the SWOT analyses, product profile, financial details, and recent developments acrossAgilent Technologies Inc, Bio-Rad Laboratories Inc, Danaher Corp, GenScript Biotech Corp, Lonza Group Ltd, Merck KGaA, New England Biolabs Inc, Oxford Expression Technologies Ltd, Promega Corp, Sartorius AG, Takara Bio Inc, Thermo Fisher Scientific Inc

Protein Expression Market Segmentation

By System
Mammalian cell expression systems
Prokaryotic expression systems
Insect cell expression systems
Yeast expression systems
Cell-free expression systems
Algal-based expression systems
By Application
Therapeutic
Research
Industrial
By End-User
Pharmaceutical companies
CROs and CDMOs
Research Institutes
Others
Geographical Analysis
North America (United States, Canada, Mexico)
Europe (Germany, France, United Kingdom, Spain, Italy, Rest of Europe)
Asia Pacific (China, India, Japan, South Korea, Rest of Asia Pacific)
South America (Brazil, Argentina, Rest of South America)
Middle East and Africa (Saudi Arabia, UAE, Rest of Middle East, South Africa, Egypt, Rest of Africa)

Protein Expression Market Companies

Agilent Technologies Inc
Bio-Rad Laboratories Inc
Danaher Corp
GenScript Biotech Corp
Lonza Group Ltd
Merck KGaA
New England Biolabs Inc
Oxford Expression Technologies Ltd
Promega Corp
Sartorius AG
Takara Bio Inc
Thermo Fisher Scientific Inc

Reasons to Buy the Protein Expression Market Study

• Deepen your industry insights and navigate uncertainties for strategy formulation, CAPEX, and Operational decisions
• Gain access to detailed insights on the Protein Expression Market, encompassing current market size, growth trends, and forecasts till 2030.
• Access detailed competitor analysis, enabling competitive advantage through a thorough understanding of market players, strategies, and potential differentiation opportunities
• Stay ahead of the curve with insights on technological advancements, innovations, and upcoming trends
• Identify lucrative investment avenues and expansion opportunities within the Protein Expression Market industry, guided by robust, data-backed analysis.
• Understand regional and global markets through country-wise analysis, regional market potential, regulatory nuances, and dynamics
• Execute strategies with confidence and speed through information, analytics, and insights on the industry value chain
• Corporate leaders, strategists, financial experts, shareholders, asset managers, and governmental representatives can make long-term planning scenarios and build an integrated and timely understanding of market dynamics
• Benefit from tailored solutions and expert consultation based on report insights, providing personalized strategies aligned with specific business needs.

TABLE OF CONTENTS

1 Introduction to 2024 Protein Expression Market
1.1 Market Overview
1.2 Quick Facts
1.3 Scope/Objective of the Study
1.4 Market Definition
1.5 Countries and Regions Covered
1.6 Units, Currency, and Conversions
1.7 Industry Value Chain

2 Research Methodology
2.1 Market Size Estimation
2.2 Sources and Research Methodology
2.3 Data Triangulation
2.4 Assumptions and Limitations

3 Executive Summary
3.1 Global Protein Expression Market Size Outlook, $ Million, 2021 to 2030
3.2 Protein Expression Market Outlook by Type, $ Million, 2021 to 2030
3.3 Protein Expression Market Outlook by Product, $ Million, 2021 to 2030
3.4 Protein Expression Market Outlook by Application, $ Million, 2021 to 2030
3.5 Protein Expression Market Outlook by Key Countries, $ Million, 2021 to 2030

4 Market Dynamics
4.1 Key Driving Forces of Protein Expression Industry
4.2 Key Market Trends in Protein Expression Industry
4.3 Potential Opportunities in Protein Expression Industry
4.4 Key Challenges in Protein Expression Industry

5 Market Factor Analysis
5.1 Value Chain Analysis
5.2 Competitive Landscape
5.2.1 Global Protein Expression Market Share by Company (%), 2023
5.2.2 Product Offerings by Company
5.3 Porter’s Five Forces Analysis
5.4 Pricing Analysis and Outlook

6 Growth Outlook Across Scenarios
6.1 Growth Analysis-Case Scenario Definitions
6.2 Low Growth Scenario Forecasts
6.3 Reference Growth Scenario Forecasts
6.4 High Growth Scenario Forecasts

7 Global Protein Expression Market Outlook by Segments
7.1 Protein Expression Market Outlook by Segments, $ Million, 2021- 2030
By System
Mammalian cell expression systems
Prokaryotic expression systems
Insect cell expression systems
Yeast expression systems
Cell-free expression systems
Algal-based expression systems
By Application
Therapeutic
Research
Industrial
By End-User
Pharmaceutical companies
CROs and CDMOs
Research Institutes
Others

8 North America Protein Expression Market Analysis and Outlook To 2030
8.1 Introduction to North America Protein Expression Markets in 2024
8.2 North America Protein Expression Market Size Outlook by Country, 2021-2030
8.2.1 United States
8.2.2 Canada
8.2.3 Mexico
8.3 North America Protein Expression Market size Outlook by Segments, 2021-2030
By System
Mammalian cell expression systems
Prokaryotic expression systems
Insect cell expression systems
Yeast expression systems
Cell-free expression systems
Algal-based expression systems
By Application
Therapeutic
Research
Industrial
By End-User
Pharmaceutical companies
CROs and CDMOs
Research Institutes
Others

9 Europe Protein Expression Market Analysis and Outlook To 2030
9.1 Introduction to Europe Protein Expression Markets in 2024
9.2 Europe Protein Expression Market Size Outlook by Country, 2021-2030
9.2.1 Germany
9.2.2 France
9.2.3 Spain
9.2.4 United Kingdom
9.2.4 Italy
9.2.5 Russia
9.2.6 Norway
9.2.7 Rest of Europe
9.3 Europe Protein Expression Market Size Outlook by Segments, 2021-2030
By System
Mammalian cell expression systems
Prokaryotic expression systems
Insect cell expression systems
Yeast expression systems
Cell-free expression systems
Algal-based expression systems
By Application
Therapeutic
Research
Industrial
By End-User
Pharmaceutical companies
CROs and CDMOs
Research Institutes
Others

10 Asia Pacific Protein Expression Market Analysis and Outlook To 2030
10.1 Introduction to Asia Pacific Protein Expression Markets in 2024
10.2 Asia Pacific Protein Expression Market Size Outlook by Country, 2021-2030
10.2.1 China
10.2.2 India
10.2.3 Japan
10.2.4 South Korea
10.2.5 Indonesia
10.2.6 Malaysia
10.2.7 Australia
10.2.8 Rest of Asia Pacific
10.3 Asia Pacific Protein Expression Market size Outlook by Segments, 2021-2030
By System
Mammalian cell expression systems
Prokaryotic expression systems
Insect cell expression systems
Yeast expression systems
Cell-free expression systems
Algal-based expression systems
By Application
Therapeutic
Research
Industrial
By End-User
Pharmaceutical companies
CROs and CDMOs
Research Institutes
Others

11 South America Protein Expression Market Analysis and Outlook To 2030
11.1 Introduction to South America Protein Expression Markets in 2024
11.2 South America Protein Expression Market Size Outlook by Country, 2021-2030
11.2.1 Brazil
11.2.2 Argentina
11.2.3 Rest of South America
11.3 South America Protein Expression Market size Outlook by Segments, 2021-2030
By System
Mammalian cell expression systems
Prokaryotic expression systems
Insect cell expression systems
Yeast expression systems
Cell-free expression systems
Algal-based expression systems
By Application
Therapeutic
Research
Industrial
By End-User
Pharmaceutical companies
CROs and CDMOs
Research Institutes
Others
12 Middle East and Africa Protein Expression Market Analysis and Outlook To 2030
12.1 Introduction to Middle East and Africa Protein Expression Markets in 2024
12.2 Middle East and Africa Protein Expression Market Size Outlook by Country, 2021-2030
12.2.1 Saudi Arabia
12.2.2 UAE
12.2.3 Oman
12.2.4 Rest of Middle East
12.2.5 Egypt
12.2.6 Nigeria
12.2.7 South Africa
12.2.8 Rest of Africa
12.3 Middle East and Africa Protein Expression Market size Outlook by Segments, 2021-2030
By System
Mammalian cell expression systems
Prokaryotic expression systems
Insect cell expression systems
Yeast expression systems
Cell-free expression systems
Algal-based expression systems
By Application
Therapeutic
Research
Industrial
By End-User
Pharmaceutical companies
CROs and CDMOs
Research Institutes
Others

13 Company Profiles
13.1 Company Snapshot
13.2 SWOT Profiles
13.3 Products and Services
13.4 Recent Developments
13.5 Financial Profile
List of Companies
Agilent Technologies Inc
Bio-Rad Laboratories Inc
Danaher Corp
GenScript Biotech Corp
Lonza Group Ltd
Merck KGaA
New England Biolabs Inc
Oxford Expression Technologies Ltd
Promega Corp
Sartorius AG
Takara Bio Inc
Thermo Fisher Scientific Inc

14 Appendix
14.1 Customization Offerings
14.2 Subscription Services
14.3 Related Reports
14.4 Publisher Expertise

By System
Mammalian cell expression systems
Prokaryotic expression systems
Insect cell expression systems
Yeast expression systems
Cell-free expression systems
Algal-based expression systems
By Application
Therapeutic
Research
Industrial
By End-User
Pharmaceutical companies
CROs and CDMOs
Research Institutes
Others
Countries Analyzed
North America (United States, Canada, Mexico)
Europe (Germany, France, United Kingdom, Spain, Italy, Rest of Europe)
Asia Pacific (China, India, Japan, South Korea, Rest of Asia Pacific)
South America (Brazil, Argentina, Rest of South America)
Middle East and Africa (Saudi Arabia, UAE, Rest of Middle East, South Africa, Egypt, Rest of Africa)